This report, from ECIIA (European Confederation of Institutes of Internal Auditing) explores five thematic risks – geopolitical uncertainty, climate change, organisational culture, cyber and data risk, and digitalisation and artificial intelligence. It outlines those challenges in detail and offers practical advice and know how about how to help organisations adjust to this new reality. There are few obvious, easy answers to these problems. But internal auditors are uniquely placed to play their part in developing long-term solutions that have a real impact on organisations and the communities they serve. They need to secure from the board the resources and remit to tackle the most pressing risks with urgency.